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Autonomic & Metabolic Control in Obesity and Sleep Apnea


Studies of Autonomic & Metabolic Control in Obesity and Sleep Apnea

Epidemiological studies in humans have demonstrated close associations among sleep apnea, systemic hypertension, Type 2 diabetes and obesity. Animal and some human studies suggest mechanistic links between metabolic and autonomic control in obese individuals, and that sleep apnea modulates these causal pathways. Dr. Khoo and his team have conducted several studies to determine whether certain autonomic indices may be useful as noninvasive biomarkers or early detectors of the “metabolic syndrome” in obesity.

Representative publications: